Immunological Issues + Fertility

Your immune system is a complex network of cells, tissues, and organs that work together to protect your body from attacks of disease and illness. Tiny microbes target the human body and can cause infections. Your immune system is the main defense of your body against getting sick. However, occasionally, the body misses the target and attacks itself rather than these microbes, even after conception has occurred. Immunological issues can cause infertility. Learn more below.

Signs of Immunological Issues

Most couples looking to conceive will see a Reproductive Endocrinologist, a doctor specializing in fertility. Although, couples with certain symptoms/signifiers may want to see a Reproductive Immunologist instead. When should you see a Reproductive Immunologist?

You should see a specialized doctor if you are displaying these symptoms:

  • 2 or more miscarriages after the age of 35
  • 2 or more IVF failures after the age of 35
  • 1 failed IVF failure before the age of 35
  • A blighted ovum

Recurrent miscarriages can be emotionally and physically taxing. Figuring out the cause of these miscarriages can help to prevent it from happening in the future. These are just a few possible reasons behind why a miscarriage is happening.

Embryo Signaling

Once conception has taken place, the embryo must signal to the mother’s immune system that it is a friendly visitor and not a foreign enemy. When embryo signaling fails, the immune system will attack the embryo. A woman’s immune system can also fail to respond to the signal from the embryo causing the embryo to fail to grow and die.

Read: Can you improve your fertility with meditation?


After an embryo has been recognized as part of the mother’s body, blood begins pumping to the fetus delivering oxygen and other necessary nutrients. However, when Thrombophilia affects the body, the blood begins clotting, depriving the fetus of the oxygen and nutrients it needs to survive.

Read: What is the endometrium and how does it affect implantation?

Systemic Enzyme Treatment

In the case of a mother’s immune system rejecting the fetus, Systemic Enzyme Treatment might help. Systemic Enzymes can reduce the immunological response allowing the fetus to grow to term. Consult with your doctor if you believe that this is the right treatment for you.

When a mother’s own body is rejecting an embryo, it’s important to identify the exact reason it’s happening so that doctors can address it and take steps to fixing it.

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